Enzalutamide Capsules 40 mg

Find Enzalutamide 40 mg capsules Cost, Uses and Substitutes.

Generic Name: Enzalutamide, Brand (Trade) Name: Xtandi

Other Names: Bdenza, Dacihep, Enzamide

About Enzalutamide

Enzalutamide is a medicine of the class of anti-androgen or anti-testosterone. It blocks the effects of testosterone in our bodies. When a patient has prostate cancer, they are diagnosed with Enzalutamide to prevent further cancer growth by blocking the impacts of testosterone in our body.

Enzalutamide (Xtandi) 40 mg cost/price

Enzalutamide (Xtandi) 40 mg costs approximately $3000 in India for 112 tablets. Check out our website to see where you can buy these medications. Patients do not need to go to the store to "buy Xtandi (Enzalutamide) 40 mg Capsule." Enzalutamide (Xtandi) 40 mg Capsule is available in capsule or tablet form.

If you want to get Xtandi (Enzalutamide) 40 mg Capsule online from India at a low cost, you may do so through (your website name). We will contact you after your request has been submitted. We ship Xtandi (Enzalutamide) 40 mg Capsules to Beijing, Hong Kong, the United Kingdom, Moscow, the United States, the United Arab Emirates, and other countries. The Enzalutamide (Xtandi) 40 mg cost/price depends upon your country.

Uses of Enzalutamide 40 mg Capsules

Enzalutamideis used to treat men with prostate cancer that has progressed to other parts of their bodies after being aided by some medicinal and surgical procedures that lower testosterone levels. It is also used to treat Enzalutamide prostate cancer in men who have not responded to medicinal or surgical procedures that reduce testosterone levels. Enzalutamide belongs to the class of drugs known as androgen receptor inhibitors. It acts by inhibiting the effects of androgen (a male reproductive hormone) on cancer cell proliferation and spread.

How do you take enzalutamide (Xtandi)?

Enzalutamide is available as a pill or capsule to be taken orally. It is consumed daily once a day, with or without food. Every day, take enzalutamide around the same time. Follow your prescription label's instructions completely, and ask your doctor or pharmacist to explain any parts you don't understand. Enzalutamide should be taken exactly as prescribed. Do not take more or fewer doses of it, or take it more frequently than your doctor has suggested.
Do not crush, chew, divide, dissolve, or open the tablets or capsules; instead, swallow them whole.
If you suffer major adverse effects while using enzalutamide, your doctor may advise you to stop taking it for a short period or reduce your dose. Talk to your doctor about how you're feeling during your enzalutamide treatment.
If your doctor has prescribed another medication to treat your prostate cancer, such as degarelix (Firmagon), goserelin (Zoladex), histrelin (Supprelin LA, Vantas), leuprolide (Eligard, Lupron, in Lupaneta Pack), or triptorelin (Trelstar, Triptodur), you must continue to take this medication during your enzalutamide treatment.
Even if you feel fine, keep taking enzalutamide. Do not discontinue enzalutamide without first consulting your doctor.

Enzalutamide Capsules side effects

Enzalutamide may have unwanted side effects. Inform your doctor of any of the following symptoms you are facing.

  • weakness
  • tiredness
  • joint pain
  • muscle weakness or stiffness
  • weight loss
  • loss of appetite
  • loss of appetite
  • dizziness
  • burning or tingling in the arms, hands, or feet
  • Loss of touch sense
  • hot flashes
  • difficulty falling asleep or staying asleep
  • anxiety
  • difficulty remembering, thinking, or paying attention
  • diarrhoea
  • diarrhoea
  • itching
  • dry skin
  • nosebleeds
  • frequent urination
  • taste changes

Some of the negative effects can be severe. If you suffer any of the following symptoms, contact your doctor or seek emergency medical attention:

  • seizures
  • headache; confusion; or vision changes
  • swelling on the face, tongue, lips, throat, arms, legs, hands, or feet
  • Infections like fever, cough, sore throat
  • chest pain
  • shortness of breath
  • pain in the back, muscles, and/or legs
  • pain in the back, muscles, and/or legs
  • difficulty controlling urination or bowel movements
  • difficulty controlling urination or bowel movements
  • falling
  • broken bones or fractures
  • hallucination
  • breast enlargement in men
  • pink or red urine

Other adverse effects of enzalutamide are possible. Contact your doctor if you have any unusual adverse effects while using this medication. If you have a major side effect, you or your doctor should notify the Food and Drug Administration (FDA).

If you suffer from back pain, shoulder joint pain, knee pain, soreness in arms and legs, neck pain, or yellow urine, consult your doctor as soon as possible. As a result of the side effects of Enzalutamide, the blood pressure of the consumers may rise. Keep your blood pressure checked regularly. Consult your doctor if you find your blood pressure level very high. The severe side effects of this medicine include: headache, seizure, sudden vision changes, decreased alertness, signs of a having a heart attack (such as chest/jaw/left arm pain, mental/mood changes (such as memory problems, confusion), shortness of breath, unusual sweating). The use of this medicine may lower the immunity of our bodies. So our body becomes prone to lots of infections. Contact your doctor if you are suffering from very severe diseases. Also, any sign of disease must be severely dealt with. Having severe allergic reactions to this medicine are not shared. Not many people are affected by the allergy from this medicine. Still, if you suffer from allergic reactions including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing, contact your doctor soon.

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Enzalutamide Capsules Mechanism of Action

Enzalutamideis a competitive androgen receptor inhibitor that affects several stages of the signalling cascade. It can block androgen binding to its receptor, nuclear translocation of the androgen receptor, and subsequent interaction with DNA. As a result, prostate cancer cell proliferation slows, leading to apoptosis and decreased tumour volume.

Enzalutamide 40 mg Dose

Missed Dose

If ever you forget to consume your medicine throughout the day, then consume it whenever you remember, just remember to take it only in 24hrs, if it takes longer than that, do not take medicine. And continue your doses from the second day, do not accidentally consume medicine twice a day.

Overdose

Get emergency medical help or contact a doctor if you suspect an overdose.

Precautions while taking Enzalutamide

Before taking enzalutamide

If you are allergic to enzalutamide, any other medications, or any of the substances in enzalutamide tablets or capsules, notify your doctor and pharmacist. For a list of the ingredients, see your pharmacist or the manufacturer's information for the patient.

Inform your doctor and pharmacist about any prescription and non-prescription drugs, vitamins, or nutritional supplements you are now taking or plan to use. Make sure you include any of the following: Warfarin (Coumadin, Jantoven), carbamazepine (Carbatrol, Equetro, Tegretol, and others), clopidogrel (Plavix), cyclosporine (Gengraf, Neoral, and Sandimmune), dihydroergotamine (D.H.E. 45, Migranal), ergotamine (in Migergot, in Cafergot), fentanyl (Actiq, Duragesic (Prograf).

Your doctor will adjust your dosage according to your health condition, if you see anyenzalutamide side effects, then the dosage of the medicine is reduced by monitoring it.

Many other drugs may interact with enzalutamide, so be sure to inform your doctor about anything you're taking, even if it's not on this list.

Inform your doctor if you have or have ever had seizures, a brain injury, a brain tumour, a brain arteriovenous malformation (an abnormal connection between arteries and veins in the brain that forms before birth and may cause bleeding in the brain), Broken bones, osteoporosis (a condition in which the bones grow thin and weak and break easily), diabetes, high cholesterol levels, high blood pressure, heart disease, or a stroke or ministroke are all possibilities.

You should be aware that enzalutamide is only prescribed to men. Women should avoid using this prescription, especially if they are pregnant or may become pregnant, or if they are breastfeeding. Women, particularly those who are or may become pregnant, should avoid handling enzalutamide capsules. Enzalutamide may harm the foetus if taken by pregnant women. If a pregnant woman uses enzalutamide, she should contact her doctor right away.

This medicine only reduces male fertility. however, assume that your female spouse cannot become pregnant. If your partner is pregnant, you must use a condom every time you have sex while on enzalutamide and for three months following your last dosage. If your partner is not pregnant but could get pregnant during therapy, you must use effective birth control whenever you have sex throughout treatment and for 3 months after your last dosage. Do not consume Enzalutamide and alcohol at a time, it cause serious problem.

Tell your doctor or dentist that you are taking enzalutamide if you are undergoing surgery, including dental surgery.

Enzalutamidelife expectancyis nearly 12 months. It has the potential to cause seizures. Do not drive or operate heavy machinery until you have determined how this drug affects you.

Missed dosage – Enzalutamide

As soon as your dose is missed, consume it as soon as you remember it. If you don't recall until the next day, omit the missing dose and stick to your regular dosing plan. Do not take more than one dose in a single day, and do not duplicate the dose to make up for a missed one.

Storage

This medicine comes in a bottle, you only have to keep it in that bottle. While travelling anywhere, carry it in the bottle itself. After consuming the medicine, tightly close the lid of the bottle, and keep it away from small children.

Keep it at ambient temperature and away from sources of extreme heat and moisture (not in the bathroom).

Because many containers contain medications, it is vital to keep all medication out of the sight and reach of children (such as weekly pill minders and those for eye drops, creams, patches, and inhalers).

To keep small children safe from poisoning, always lock the safety caps and immediately place the medication in a safe location out of their sight and reach.

If the medicine survives or expires, then dispose of them immediately, so that small children, pets or any person cannot accidentally consume it.

However, you should not flush this medication. Instead, a medicine take-back programme is an ideal approach to dispose of your medicines. Learn about take-back initiatives in your neighbourhood by speaking with your pharmacist or contacting your local garbage/recycling department.

Enzalutamide 40 mg brand

Enzalutamideis composition of 11 types of components which are basically used to treat prostate cancer and male fertility. Enzalutamide 40 mg brand name are Xtandi®, ENZANA, CAPMIDE, BDENZA, XYLUTIDE, OBNYX, ENZAMIDE, ENCRPC, AZEL, ADLEAP, GLENZA etc.

Enzalutamide (Xtandi) 40 mg price in India

Enzalutamide (Xtandi) 40 mg costs approximately $3000 in India for 112 tablets. The drugabiraterone andEnzalutamide(Xtandi) 40mg Soft Capsule is used to treat prostate cancer. It may also be used to treat another disease similar to cancer or male fertility as determined by the doctor. It works by suppressing the effects of masculine hormones like testosterone.

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Some FAQs about Enzalutamide (Xtandi) 40 mg

Yes, Swelling (edema) in hands, arms, feet, or legs and tingling, burning, pricking, or numbness of the skin.

The most common side effects among participants taking enzalutamide were fatigue, constipation, and back and joint pain.

. No, Xtandi doesn't cause hair loss.

In addition, enzalutamide is primarily eliminated by hepatic metabolism, while renal excretion is an insignificant elimination pathway for enzalutamide and its active metabolite, N-desmethyl enzalutamide. Exposure to enzalutamide active moieties is not affected by food or baseline mild or moderate hepatic impairment.

Enzalutamide is used to treat prostate cancer that has spread to other parts of the body in men and who have been helped by certain medical and surgical treatments that decrease testosterone levels.

XTANDI was first approved by the FDA in 2012 for the treatment of patients with metastatic CRPC who had previously received docetaxel, and was granted approval in 2014 for chemotherapy-naïve men with metastatic CRPC.

Enzalutamide, an androgen receptor antagonist, enhances myeloid cell–mediated immune suppression and tumor progression.

Potential to cause seizures, especially in those predisposed to seizure activity. The toxicological, physical and other potential hazards associated with this compound have not been fully characterized. Should avoid ingestion, inhalation, skin and eye contact.

There are amlodipine,
Aspirin,
Aspirin Low Strength (aspirin),
Atorvastatin,
Eliquis (apixaban),
Furosemide,
Gabapentin,
Hydrochlorothiazide.

Be careful before you drive or use any machines or tools until you know how XTANDI affects you. XTANDI may have a moderate influence on your ability to drive or use any tools or machinery. Seizures have been reported in patients taking XTANDI. If you are at higher risk of seizures, talk to your doctor.

XTANDI comes in both capsule and tablet formulations. Capsules are available in 40 mg capsules only. Smaller‑sized tablets are available in 2 dosage strengths: 40 mg and 80 mg tablets, giving you more options to meet your daily dose.

XTANDI can be taken with or without food. Swallow XTANDI capsules or tablets whole. Do not chew, dissolve, or open the capsules.

Xtandi works by blocking the action of androgens at the androgen receptor - reducing how often androgens can connect with the receptor - which helps prevent prostate cancer cells from growing and spreading.

XTANDI is FDA-approved to treat 3 forms of advanced prostate cancer.
61% LOWER. CHANCE. Metastatic castration-sensitive prostate cancer (mCSPC) ...
83% LOWER. CHANCE. Metastatic castration-resistant prostate cancer (mCRPC) ...
71% LOWER. CHANCE. Non-metastatic castration-resistant prostate cancer (nmCRPC)

The study suggests that enzalutamide can increase life expectancy: A quarter of the men had passed away within about 17 months in the active surveillance group, and within about 22 months in the enzalutamide group.

A progression-free survival rate of 65% was observed at 12 months among Xtandi-treated patients compared with a 14% rate among those receiving placebo. Treatment with Xtandi also helped delay the need for cytotoxic chemotherapy.

The drug, enzalutamide, stops working after four or five months and appears to have a dual function that later turns the cancer into a relentless aggressor. The new research indicates how to block the harmful side effects of the drug, at least in mice.

Although enzalutamide appeared to be effective regardless of whether men had high- or low-volume disease, one apparent differentiating factor was planned early treatment with docetaxel.

Our results demonstrated that enzalutamide was more efficacious than abiraterone for patients with metastatic castration-resistant prostate cancer, but was associated with a significantly elevated risk of side effects, particularly fatigue.

Enzalutamide may cause high blood pressure. Your doctor should monitor your blood pressure regularly while you are taking this medication. Bone health/fractures: This medication may increase the risk of bone fractures.

Enzalutamide is only for use in men. You should not take this medication, especially if you are or may become pregnant or are breastfeeding. Enzalutamide may harm the fetus (unborn baby).

Enzalutamide is the generic name for the trade name drug Xtandi®.

Yes. 100% of Medicare prescription drug plans cover this drug.

Store Xtandi® at room temperature (68-77 degrees F or 20-25 degrees C). Keep the container closed tightly, dry, and out of the reach of children.

Enzalutamide has not been linked to cases of acute liver failure, chronic hepatitis or vanishing bile duct syndrome.

In the bicalutamide-controlled study, the most common adverse reactions (≥ 10%) reported in XTANDI-treated patients were asthenia/fatigue, back pain, musculoskeletal pain, hot flush, hypertension, nausea, constipation, diarrhea, upper respiratory tract infection, and weight loss.

Blockage of the arteries in the heart (ischemic heart disease) that can lead to death has happened in some people during treatment with XTANDI. Your doctor will monitor you for signs and symptoms of heart problems during your treatment.

Xtandi can reduce your appetite. In clinical studies, up to 12% of people taking Xtandi had weight loss. Of those taking a placebo (treatment with no active drug), up to 8.5% had weight loss.

In clinical studies, up to 51% of people taking the drug felt fatigued or tired. Of those taking a placebo (treatment with no active drug), 44% had the same result. If you feel fatigued during Xtandi treatment, talk with your doctor.

In clinical studies, up to 51% of people taking the drug felt fatigued or tired. Of those taking a placebo (treatment with no active drug), 44% had the same result. If you feel fatigued during Xtandi treatment, talk with your doctor.

Enzalutamide is usually taken as four tablets, once a day. You should take the tablets at the same time each day and swallow them whole with water. You can take the tablets with or without food.

Yes. Other side effects include: lower respiratory tract infection, pneumonia, pulmonary infection, altered mental status, amnesia, bronchitis, cognitive dysfunction, falling, hypertension, hypoesthesia, and memory impairment.

A progression-free survival rate of 65% was observed at 12 months among Xtandi-treated patients compared with a 14% rate among those receiving placebo. Treatment with Xtandi also helped delay the need for cytotoxic chemotherapy.

At the interim analysis (after a median follow-up of approximately 22 months), 28 percent of men in the enzalutamide group had died, compared with 35 percent of men in the placebo group. Men who received enzalutamide experienced a 29 percent reduction in the risk of death compared with those who received placebo.

Enzalutamide is used to treat prostate cancer that has spread to other parts of the body in men and who have been helped by certain medical and surgical treatments that decrease testosterone levels.


Headache.
Hives, itching, skin rash.
Irritation.
Joint pain, stiffness, or swelling.
Swelling of the eyelids, face, lips, hands, or feet.
Trouble breathing or swallowing.
Unusual drowsiness, tiredness, weakness, or feeling of sluggishness.

Treatment with Xtandi resulted in a median overall survival time of 18.4 months (95% CI 17.3 to not yet reached) compared with 13.6 months (95% CI 11.3 to 15.8) in the placebo recipients.

Enzalutamide is an oral androgen-receptor inhibitor that prolongs survival in men with metastatic castration-resistant prostate cancer in whom the disease has progressed after chemotherapy.

Enzalutamide is in a class of medications called androgen receptor inhibitors. It works by blocking the effects of androgen (a male reproductive hormone) to stop the growth and spread of cancer cells.

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All the contents present on the website are solely for informational purposes. Thereby, the information on the website isn’t meant to be a substitute for professional medical advice, treatment, and/or diagnosis. Please seek professional advice from a doctor/physician for queries regarding a medical condition. This website, by no means, are responsible for consequences caused due to avoiding professional medical advice.
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